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Our evaluation of the cohort is that the medical exercise of MCLA-129 in second line head and neck cancer seems substantially inferior to that of our direct asset petosemtamab, and only on par with other EGFR or cetuximab-dependent monoclonal or bispecific antibodies as monotherapy in a similar environment. We consider this efficacy is insufficient to warrant even more enhancement in head and neck cancer.
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The third century Advert marked a significant decrease in Asia stemming partly from epidemic ailment, starting Together with the Antonine plague, the indiscipline of regional soldiers and in addition the diminishing cases of voluntary civic generosity.
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The truth is, Asia province was exclusive in that it had been one of many handful of ungarrisoned provinces in the empire. Although no total legions have been ever stationed inside the province, that's not to mention that there was no armed service existence in any respect.[11]
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† Italy was hardly ever constituted check here to be a province, instead retaining a special juridical status until Diocletian's reforms.